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VOL. 8, ISSUE 2 (2023)
Catharanthus roseus anti-inflammatory action: A systematic review protocol of in vivo and in vitro studies
Authors
Eka Santi, Windy Yuliana Budianto, Widya Nursantari, Indrya Anggita Sari, Fatma S Ruffaida
Abstract
Catharanthus roseus is a plant that has been traditionally used for medicinal purposes and
belongs to the Apocynaceae family. This plant thrives in tropical and subtropical
climates all over the world. A variety of bioactive chemicals that have
therapeutic benefits can be found in plants. C. roseus is known for its
significant biological effects, such as antibacterial, antiviral, antifungal,
antioxidant, and anticancer properties. The purpose of this systematic review
is to meticulously analyze scientific evidence of the anti-inflammatory
properties exhibited by Catharanthus roseus through in vivo and in
vitro studies. The review aims to answer questions regarding the
effectiveness of different plant extracts and their impact on acute
inflammation using experimental models. The guidance of Preferred Reporting
Items for Systematic Review and Meta-analysis (PRISMA) will be adhered to in
conducting this Systematic Review. Rayyan will be used in the process of
selecting evidence and duplicate articles will be removed. Data will be
collected using customized data extraction in spreadsheet. the Systematic
Review Center for Laboratory Animal Experimentation (SYRCLE) will be utilized
will be used to assess risk of bias. The results session will present the data
synthesis, and some authors may be contacted for unclear or missing data.
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Pages:8-10
How to cite this article:
Eka Santi, Windy Yuliana Budianto, Widya Nursantari, Indrya Anggita Sari, Fatma S Ruffaida "<i>Catharanthus roseus </i>anti-inflammatory action: A systematic review protocol of <i>in vivo</i> and <i>in vitro</i> studies". International Journal of Medicine Research, Vol 8, Issue 2, 2023, Pages 8-10
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