Background: Chronic pain, one of the leading causes of suffering and disability worldwide, is becoming an important field in medical as well as behavioural sciences. A variety of chronic pain syndromes lie on the spectrum of medically unexplained syndromes, causing dysfunction and reduced quality of care. Because of its multi-faceted nature, involving physiological, psychological and social factors, chronic pain warrants extensive research to understand and guide comprehensive interventions. Materials and Methods: A cross sectional, exploratory, comparison group research design was employed. Sixty participants were recruited through invitation on social media platforms as well as from the pain clinic in a tertiary care hospital of North India, which were allocated to the primary chronic pain (n=30) and secondary chronic pain (n=30) groups as per the inclusion/ exclusion criteria. Telephonic interview was conducted with the consenting participants and Trauma antecedent’s questionnaire, Toronto alexithymia scale (Hindi) and Short Form-36 were administered with eligible participants in both the groups. Results: Significant differences were found in the two groups on age, marital status, and number of pain locations, reporting of fatigue, lack of freshness after sleep and depressed mood/irritability. Results revealed significant differences on measures of trauma antecedents, alexithymia and quality of life between primary chronic pain group and secondary chronic pain group (p< 0.05). Conclusions: Primary chronic group showed higher levels of trauma exposure, emotional regulation as well as lower quality of life as compared to secondary chronic pain group.