Nephrolithiasis is common worldwide; this is the third commonest disorder of urinary tract after UTI and prostatic hyperplasia. The following case report is of ureteric calculi with hydrouteronephrosis treated successfully with individualized homoeopathic medicine selected on the basis of totality of symptoms. This case report illustrates positive role of homoeopathic treatment in managing cases of renal stones. Case Summary: A 36 years old female patient reported to the OPD with the complaint of pain in right lumbar region radiating from right loin to right groin area. After considering the totality of the patient Lycopodium clavatum 200 was prescribed. The patient responded well with homoeopathic treatment, the pain subsides and stone was expelled completely. Hence, this emphasizes the role of homoeopathy in the treatment of urolithiasis.