Patients with age-related macular degeneration (AMD) are discovered at very late stage of the disease when they usually complain of central blurring of vision and decrease ability to read in dim light. It develops due to many causes such as poor circulation in choroidal vessels. Optical coherence tomography (OCT) was proved as a vital investigation in the diagnosis and improving the efficiency of clinical (dynamic) monitoring of patients with AMD. Prospective case series study was performed on 150 patients, through firm follow up, investigations and examinations over a period of time. We noticed that patients develop AMD changes during their visits