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International Journal of
Medicine Research
ARCHIVES
VOL. 5, ISSUE 1 (2020)
Human chorionic ganadotropllin level as predictor of preeclampsia in Al-Zahra teaching hospital
Authors
Dr. Entessar Abd Al-Rassol, Dr. Saba Fouad Abd Al-Razak
Abstract
Background: Preeclampsia is a form of hypertension disorder of pregnancy is characterized by development of concurrent hypertension and proteinuria sometimes progressing into a multiorgan cluster of varying clinical feature. Many biochemical markers of preeclampsia have been recognized in maternal serum one of them is serum Beta human chorionic gonadotrophin. Aim of the study: To evaluate the level of HCG in the detection of severity of preeclampsia Study & design: Prospective cross section study of maternal human HCG level in patient with preeclampsia comparison with the control group in AL- Zahra teaching hospital Material& Method: The patient included in this study will be divided into two group, 50 control group who are normotensive and 50 preeclamptic patient which further divided into mild and sever A complete clinical history was taken from each woman including maternal age, parity, gestational age, and other questions related to this condition and blood sample was taken for biochemical and hematological investigation. the blood samples were centrifuged for 15 minutes, sera collected &stored in deep freeze until the assay was performed in the same laboratory by ELISA (enzyme linked immune sorbent assay) and sent for liver function test, renal function test, complete blood picture and HCG Results: There is no significant difference were observed in age and parity of preeclamptic group in comparison with the control group there is significant in relationship in the systolic, diastolic blood pressure and body mass index between preeclampsia group &the control group ( and the SGOT, SGPT, blood urea serum creatinine, serum uric acid significantly increase in preeclampsia group in comparison with the control group( pevalue <0.001) but there is no significant difference in the level of ALP &TSB between 2 groups and there is significant increment in the hCG level between preeclampsia and control group and there is further significant increment in the hCG level between sever preeclampsia and mild preeclampsia Conclusion: Serum HCG level may be involved in the pathophysiology of preeclampsia and it can be used as a marker to detect the severity of preeclampsia.
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Pages:109-113
How to cite this article:
Dr. Entessar Abd Al-Rassol, Dr. Saba Fouad Abd Al-Razak "Human chorionic ganadotropllin level as predictor of preeclampsia in Al-Zahra teaching hospital". International Journal of Medicine Research, Vol 5, Issue 1, 2020, Pages 109-113
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