A study was carried out on 34 year old married male patient, who was diagnosed with bilateral nephrolithiasis associated with some metabolic disturbances like hypercalciuria, hyperoxaluria, hyperuricemia and vitamin D deficiency. Patients have history of recurrent stone formation. All mentioned said metabolic disorders are interlinked with each other. Patient was put on Unani medicine like Mudri-e-Boul Advia, Muffatit-e-Hissat Advia, Vitamin-D and Vitamin-B6 supplement and some strict dietary advices for two months and patient got improved.