Aim: The present study was carried out to assess the possible relation between serum PRL levels and frequency of T. gondii infection in humans.

Material & methods: A prospective study was conducted in the Department of General Medicine, Mamata Medical College, Khammam, for the period of 6 months. Men and women aged 15–55 years with no clinical complications participated in this cross-sectional study. A total of 500 blood samples were collected from individuals who had been referred for PRL measurement.

Results: Of the total participants, 70% were women and 30% men. Of 500 blood serum samples, 162 samples (32.4%) had anti- Toxoplasma IgG. Participants were divided into five age groups of below 19, 20–30, 30–40, 40–50, and above 50 years. According to the age of participants, the prevalence of anti- Toxoplasma IgG in 500 blood serum samples was as follows: <19 age group, (21.7%); 20–30, (32.43%); 30–40, (34.85%); 40–50 age group, (30.90%); and >50 age group, (42.10%). Of 350 serum samples of women, 68 (28.3%) had anti-Toxoplasma IgG while of 150 serum samples of men 57 (38%) had anti- Toxoplasma IgG antibody. In total, of 343 serum samples, 245 (49%) were considered as normal range of PRL, 20 (4%) and 235 (45%) samples were considered as hypoprolactinemia and hyperprolactinemia, respectively.