Context: Emotional intelligence is the ability to control negative emotions. Psychological wellbeing is an important component of quality of life. There are very few studies analysing the association of emotional intelligence and quality of life in oncology patients. Aims: To analyse the emotional intelligence of the patients, analyse their quality of life and explore if there is any relationship between the them. Settings and Design: This was a cross sectional study conducted in Kamineni Academy of Medical Sciences and Research Centre. A total of 105 oncology patients were recruited for the study between January 2018 and March 2018. Methods and Material: For analysing the emotional intelligence, the abridged version of Bar-On EQ inventory was used. EORTC QLQ C30 quality of life questionnaire was used to analyse the quality of life. Statistical analysis used: Multiple regression was conducted to find out the impact of Emotional Intelligence on different variables of Quality of life Results: Emotional intelligence was higher with advancing age. Analysis clearly showed that patients with higher emotional intelligence had better emotional, social functioning and quality of life. Conclusions: Cancer is a devastating diagnosis with both physical and psychological distress. For the patients to fare through the diagnosis and management well, Emotional intelligence is an important aspect affecting the quality of life.