Introduction: Hepatitis C virus (HCV) infection poses a significant public health problem worldwide. Previous studies have demonstrated the influence of HCV on hematological and liver function parameters. However, further investigation is necessary to understand the comprehensive profile of these alterations.

Aim and Objectives: This study aimed to investigate the hematological profiles and liver function parameters in Hepatitis C patients in a tertiary hospital setting, comparing these to the standard norms and between patients with acute and chronic infections.

Material and Methods: A cross-sectional study was conducted with patients diagnosed with Hepatitis C. Data on demographics, hematological parameters (including RBC, Hb, Hct, Plt, WBC, MCV, MCH, MCHC, RDW), and liver function parameters (AST, ALT, ALP, total bilirubin, and albumin) were collected from medical records.

Results: Deviations from normal ranges were observed in most hematological and liver function parameters. Specifically, there were significant increases in liver enzymes (AST, ALT) and total bilirubin, and decreases in albumin levels, indicative of liver dysfunction. RBC, Hb, and Hct levels were slightly decreased, suggesting potential anemia in these patients. Chronic HCV patients displayed more substantial deviations in these parameters compared to their acute counterparts.