Introduction: Malaria is a significant global health concern, causing considerable morbidity and mortality worldwide. Understanding the role of hematological parameters in malarial infections is crucial for comprehending disease mechanisms. This cross-sectional study investigates alterations in hematological parameters and their clinical significance in patients with malaria.

Material and Methods: The study includes 150 malaria-diagnosed patients. Demographic data, complete blood counts (CBC), and symptom severity scores were collected. Hematological parameters, such as RBC Count, Hemoglobin, Hematocrit, Platelet Count, and WBC Count, were assessed. Mean and standard deviation values were calculated for each parameter. The study aims to shed light on the clinical implications of these hematological alterations in malaria.

Results: The study found significant hematological alterations in patients with malarial infections. Mean values for Red Blood Cell (RBC) Count, Hemoglobin, Hematocrit, Platelet Count, and White Blood Cell (WBC) Count were lower than normal ranges. Symptom severity scores for Fever, Headache, Body Pains, Chills, Rigors, and Sweating were moderately high.